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Sanguis draconis (SD), a traditional medicine for activating blood circulation and removing blood stasis, possesses multiple pharmacological activities, including anti-inflammatory, antioxidant, and tissue repair-promoting effects, with relatively low toxicity

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Furthermore, since inflammation is associated with the injury or damage of neurons (Yamanouchi et al., 2017), anti-inflammatory danggui Sini decoction could remarkably increase the amounts of Nissl bodies (the biomarker for the normal morphology of neurons) and improve the morphology of DRG cells, thus, alleviating the pathogenesis of peripheral neuropathy ( Some extracts of traditional medicines with the antioxidant activity could also be applied to overcome PIPN